Horses and Oxidative Stress

Today I was asked for my opinion on the use of Protandim with the EHV-1 outbreaks in Minnesota and New Mexico. While I have an extensive background in horses, I am not a doctor, scientist or vet (nor do I want to be). I do have a number of equine vets I trust so I solicited their input and here’s the summary:

EHV-1 is a form of vasculitis or what is more commonly referred to as inflammation of the blood vessels. It wreaks havoc with the cell structure causing damage via significant inflammation at the cellular level. This is common in most any condition that affects the human or equine body but with EHV-1 the virus attacks the central nervous system which is not equipped to expand for inflammation. This why the resulting symptomology it so severe and widespread.

Imagine you got kicked in the thigh by a horse. The resulting hematoma and swelling would be an aggravation and hurt like the dickens, but because the thigh has room to swell you likely will continue on fairly normally because it has room to accommodate the associated cellular swelling as it heals.

When EHV-1 attacks the cells in the central nervous system there is no room there to accommodate the resultant swelling. The damage becomes even more profound and wide spread as the primary functionality the central nervous system is responsible for, i.e. communicating with every system in the body and controlling all bodily functions is disrupted by the inflammation.

If the central nervous system can’t communicate with the body its only a matter of time before the body stops functioning normally.

We already know that at a cellular level Protandim causes the cell to produce its own powerful anti-inflammatory enzymes. It also reduces C-reactive protein which is a marker for inflammation in the body. In my vets opinion Protandim is an excellent addition to any treatment regime when EHV-1 has been diagnosed. Dosage is two pills per day for the acute event and for at least 90 days after the symptomology is no longer evident.

What I do know about EHV-1 is it is a dormant virus carried in all horses. The theory is it breaks out under high stress situations which is why you usually see outbreaks starting at a competition with large numbers of horses or in a horse who has just returned from a competition or other high stress event. Once it launches it is highly contagious until it runs the cycle.

Backyard horses rarely show this virus since they are rarely under the types of stress created at competitive horse events. My personal horses are all competition level equine athletes and this is just one of many reasons they have been on Protandim for four years and will always be.

Greg Dieker

3 Reasons Your Hair is Making You Look Older

While many of us are well aware of the effects of aging when it comes to our skin, it might surprise you to know that your hair—even though it may not look it—is suffering from the causes of aging as well. In fact, the causes of aging when it comes to your hair actually start taking a toll on your tresses well before you even notice the changes, and they can occur at any age.

Do your locks seem like they’re thinning? Brittle? Dry? This may all have to do with three simple factors: stress, hormones, and diet.

1. Stress

Hair loss and thinning can be triggered by stress, and the effects are often delayed by a few months. Stressful events that can cause hair loss may include a traumatic accident, the loss of a loved one, or even prolonged money troubles.

When stress is one of the causes of aging in hair, your follicles go into a sort of shock or sleep state, stopping growth for a significant period of time before new strands start to grow. The eventual growth of new hair pushes out the old hair, causing hair loss and thinning.

To fight the causes of aging in hair when it comes to delayed and acute stress, include stress management or activities that promote relaxation in your anti-aging hair care routine— yoga, meditation, or even a daily bath with a few drops of lavender oil can reduce stress, which in turn can help promote hair growth.

2. Hormones

Fluctuations in hormones may be one of the most common causes of aging hair. Hormones have an effect similar to that of stress on your hair’s health. Fluctuations can cause your body to experience stress, forcing hair growth to halt. It can also go the other way—stress can cause hormonal fluctuations, which then affect the look and feel of your strands. Some factors that may contribute to hormones as one of the causes of aging hair are hormonal contraceptives (i.e., birth control pills or hormonal intrauterine devices), pregnancy, hormone therapy, or menopause.

When it comes to hormones, there’s not much that you can add to your anti-aging hair care routine; generally speaking, these fluctuations usually pass, and your hormones should balance themselves out again. However, you can use a combination of relaxation techniques and a healthy diet to help minimize the effects. Hormone therapy is an option, but an extreme one, and anti-aging hair care usually doesn’t warrant it.

3. Anti-Aging Diet

As one of the causes of aging hair, your anti-aging diet is probably the easiest to treat. When it comes to nutritional deficiencies, it can be hard to identify exactly what you’re missing from your anti-aging hair care diet. Most often, the culprits are high cholesterol and insufficient B vitamins, iron, protein, or vitamin C. In treating nutritional deficiencies as one of the causes of aging in hair, make sure your anti-aging diet is high in B vitamins, protein, iron, and vitamin C, and try to skip fatty, fried, or pre-packaged foods.

Check out our anti-aging hair care diet for the top foods that fend off the causes of aging and promote healthy strands at any age.

When it comes to anti-aging hair care, the causes of aging are few, and they can be treated; in fact, the effects from the causes of aging when it comes to your hair are usually reversible. Because your hair is always growing and renewing itself, all you have to do is get to the root of the problem.

The Agein Team

Protandim Ingredient – Tumeric

Turmeric is well known for having health promoting effects. Doctors Health Press reported on March 24, 2014 that new research shows that the spice turmeric has age reversing properties. Turmeric is a warm, peppery spice that adds a delicious flavor to curries and which gives mustard its yellow color.

Turmeric has been used for a long time in ancient Chinese and Indian medicine as an anti-inflammatory agent and for other health properties. Curcumin is an antioxidant present in high amounts in turmeric which is the active ingredient that appears to provide turmeric with a number of potential healing abilities. A new study which has been published in the journal Cellular Physiology and Biochemistry has indicated that turmeric might provide therapeutic benefits for reversing age-related cerebrovascular dysfunction. In cerebrovascular dysfunction blood flow and circulation to the brain is impacted.

In this study rats were fed curcumin for a month. At 24 months of age male rodents were tested against a control group of younger, six-month-old rats in order to identify any impacts curcumin might exhibit. After the month of curcumin treatment an incredible restoration of the ability of blood vessels to naturally relax was noted in the aging rats. This resulted in easier blood flow and circulation to the brain. It was noted that in particular curcumin displayed the ability to increase nitrous oxide bioavailability, therefore allowing the inner blood vessels of the brain to dilate. This is associated with a lowering of cardiovascular risk and hypertension because blood can move freely through arteries.

WebMD reports turmeric is a plant which is the main spice in curry but the root of turmeric is also widely used to make medicine. Turmeric is widely used to treat inflammatory conditions such as arthritis. Turmeric is also used to treat depression and Alzheimer’s disease. Turmeric certainly is a tasty spice with many valuable medicinal properties.

5 Worst Anti-Aging Myths Exposed

The first step anyone should take when creating their personalized routine for aging well is to wipe out all the myths that surround aging, including the causes, bogus anti-aging tips, and inaccurate prevention options. Here are five of the most common myths that are holding you back from aging well.

Anti-Aging Myth #1: “Aging is all in the genes.”

Whether it’s the age spots on your hands or fine lines around the mouth, how you age has less to do with your genes and more to do with how much attention you pay to aging well. For example, even if you are conscientious about your anti-aging skin care routine and have inherited great genes, a habit like smoking can overpower all of that thanks to the toxins and poisons in cigarettes, like arsenic, formaldehyde, and carbon monoxide, that interfere with your body’s ability to continue aging well.

Don’t want those crow’s feet your mother had? Invest in a hydrating eye cream and wear full protection sunglasses. Prevention is the key to aging well, not genes.

Anti-Aging Myth #2: “It’s too late for me to start exercising.”

It is never too late to start working on an anti-aging fitness routine. In fact, studies have shown that even a brisk, 20-minute walk every day, at any age, contributes to aging well because it has the power to reduce your cholesterol as well as your risk of developing cardiovascular diseases. There’s no such thing as being too old for anti-aging fitness, because you can tailor your routine to what works for you and your body. The more exercise you do over time, the better your fitness level will be, and the better your fitness level is, the better equipped you are to continue aging well.

Along with improving your chances of aging well, anti-aging fitness also enhances your anti-aging skin care routine because as you sweat, your body is releasing toxins, along with dirt and oil on your skin’s surface. Plus, the increased blood circulation gives you a healthy glow, reduces inflammation, and improves the overall health of your skin.

Anti-Aging Myth #3: “I don’t need to wear sunscreen in the winter.”

This is a popular anti-aging skin care myth and causes the most harm to aging well when it comes to your skin. Just because you don’t see the sun or you work indoors, it doesn’t mean you’re any less susceptible to the harsh implications of the sun’s rays. UV rays actually penetrate through clouds and windows and reflect off ice and snow, making them just as much of a threat to aging well in winter as in the summer. Wearing sunscreen year-round is essential for aging well because it provides a shield against harmful UVA and UVB rays—a simple anti-aging skin care step that goes a long way.

Anti-Aging Myth #4: “My skin is oily, so I don’t need a moisturizer.”

The oil on your skin might make your skin feel “moist,” which is why the misconception of not needing a moisturizer as a part of your anti-aging skin care routine is so common. But skipping moisturizer altogether can work against your efforts toward aging well. Facial moisturizers put water, not oil, back into the skin, and the hydration from the water is what helps plump out those fine lines. If you have oily skin, it means your skin excretes excess sebum, but facial moisturizers contain ingredients that are absorbed into the skin, helping it to continue aging well over the years.

If you use other skin care products, like cleansers and exfoliants, for aging well, but then skip the moisturizer, you run the risk of drying your skin out too much, and when that happens, sebum production goes into overdrive to compensate—so you actually end up making oily skin worse. Using a moisturizer helps to keep sebum levels in check.

Anti-Aging Myth #5: “Taking multivitamins will delay the aging process.”

If all it took was popping a multivitamin to ensure aging well and avoid the natural signs of aging, anti-aging wouldn’t be a billion-dollar industry. The truth is that while multivitamins can be helpful, they only provide the bare basics of aging well; the rest is up to us. If you have a well-rounded diet, you shouldn’t need to rely so much on vitamins or anti-aging supplements. Plus, several studies have shown that taking multivitamins isn’t as effective for aging well as many people think because they don’t necessarily do much for disease prevention.

To lasting health and beauty, Agein

Alzumab vs Protandim Truescience

The Indian pharmaceutical industry is as mature as it is robust when it comes to developing generics of previously approved drugs. But to develop and bring a completely new drug, in its own class, to market is something that any developing economy should wear as a badge of pride. ALZUMAb — also known as itolizumab — that has been created, tested, and approved in India for plaque psoriasis by Bangalore-based Biocon has hit the market.

What makes this drug so special is that it is an antibody that targets a surface marker on T cells, for which no other company has developed a drug as of yet. T cells are immune cells that are instigators in various autoimmune diseases, such as rheumatoid arthritis, multiple sclerosis, and psoriasis. Psoriasis, for which this drug is currently approved in India, affects two to three percent of the world’s population.

The drug targets the CD6 surface receptor, binding to it and blocking activation of T cells in inflammatory environments within the body. The drug targets Th17 helper T cells, which were only discovered within the last six years and have been implicated in an array of autoimmune diseases. The surface receptor, CD6, is also important for T-cell migration to sites of inflammation and maturation to become pro-inflammatory.

The benefit of the drug over other antibodies that block inflammatory cytokines, which are protein cells that tell other immune cells to be activated, is that it stops the pro-inflammatory cytokines from being produced in the first place.

Phase III clinical trials using the drug for plaque psoriasis showed a remarkable reduction of symptoms after 12 weeks of treatment. The drug was compared to a placebo control in moderate to severe psoriasis patients.

Compared to other drugs that suppress the immune system, ALZUMAb was seen to be safe and had a low risk of causing infections. Additionally, patients stayed in remission for longer than they did from other treatment options. The drug is priced at a moderate $122 ($7,500 rupees) per vial, which is far lower than the many thousands of dollars that comparable biologic drugs cost in the U.S.

Side Effects
The most common side effects are:
Infusion reactions
Upper respiratory infections

Comprised of natural plant ingredients, Protandim is a patented, science-based formula that has been researched, tested and validated by renowned universities and institutions. It is the only supplement clinically proven to reduce oxidative stress in humans by an average of 40 percent in 30 days.

Protandim activates Nrf2, which communicates with cells, instructing them to do what they’re already designed to do: up-regulate “survival genes,” genes that enable cells to survive in the face of stress from free radicals and other oxidants, and down-regulate other genes to help the body function at an optimal level.

TrueScience Anti-Aging Cream provides the latest skin care technology. Its powerful anti-wrinkle formula boosts six skin-rebuilding essentials and contains the 11 ingredients effective in improving skin tone, texture and appearance. Unlock the science of anti-aging and unlock the secret of a younger-looking you with TrueScience Anti-Aging Cream.

Alzumab can’t be compared to Protandim and Truescience because Protandim Truescience is not a drug. You don’t need a prescription, or needs to get the health benefits you desire.

Protandim is $40 for a 30 day supply and Truescience is $70 for a 60 day supply. So for $110 You get the complete inside out protection and not just for skin related diseases but protection from every disease in the body.

#Alzumab vs #Protandim #Truescience #guttatepsoriasis #psoriasis